MEDICINAL TURMERIC – A NATURAL WAY TO FIGHT COVID-19

Medicinal Turmeric has been used for centuries in Asia, and today is endorsed around the world as a dietary supplement too. It has super pharmacological properties and the world believes in it too. Curcumin the polyphenol found in medicinal turmeric makes this spice the best anti-inflammatory and anti-oxidant found in nature.

Medicinal Turmeric is also believed to have other properties which include:

Anti-proliferative

Anti-microbial

Neuro-protective

Cardio-protective

Wound healing

Curcumin has been found to be valuable in other viral disorders such as AIDS due to its inhibitory action against HIV protease and integrase along with its synergistic action on other healing drugs. It has also been shown to constrain other viruses such as hepatitis B, hepatitis C, zika, chikungunya and dengue. Respiratory anguish syndrome with fulminant hypercytokinaemia and multi-organ failure is the foremost cause of mortality with COVID‐19. Curcumin has been found to weaken influenza A virus‐prompted lung tissue injury by filibustering nuclear factor κB signalling and inhibiting the production of inflammatory cytokines. Curcumin in medicinal turmeric is a natural ligand of peroxisome proliferator‐activated receptor‐γ, which curbs the inflammatory process by plummeting cytokine production; therefore play a similar role in shielding against lung injury associated with COVID.

Curcumin As An Anti-Viral

Curcumin in medicinal turmeric has been shown to impede the duplication of some types of virus, including dengue virus, hepatitis B and Zika virus. The natural poly phenol has also been found to have a number of noteworthy biological effects, including antitumor, anti-inflammatory and anti-bacterial activities. Curcumin is also a great natural choice as an anti-viral due low or no side effects.

Curcumin As An Anti-Inflammatory

Curcumin is strongly and very powerful anti-inflammatory. In fact, it’s so powerful that it matches the effectiveness of some anti-inflammatory drugs, without the side effects. Curcumin in medicinal turmeric effectively blocks NF-kB, a molecule that travels into the nuclei of your cells and turns on genes related to inflammation. NF-kB is believed to play a major role in many chronic diseases and curcumin thwarts it naturally.

Curcumin As An Antipyretic

Curcumin showed a significant antipyretic effect by diminishing the rectal temperature. Studies reveal that curcumin in medicinal turmeric has an inhibitory impact on prostaglandins. Curcumin impedes the upsurge of glutamate, hydroxyl radicals and PGE2 in the hypothalamus and lessens fever during LPS-induced systemic inflammation.

Curcumin & Acute Lung Injury

It appears that curcumin attenuates acute lung injury, probably through improving oxidative stress and inhibiting nuclear factor-κB-mediated expression of inflammatory cytokines. Thus, curcumin may be an alternative therapy for improving the outcomes of ischemia–reperfusion-induced lung injury.

Curcumin and ARDS

Acute Respiratory Distress Syndrome (ARDS) is a clinical syndrome characterized by diffuse alveolar impairment usually secondary to an intense host inflammatory response of the lung to a pulmonary or extra pulmonary transmittable or non- transmittable harm often leading to the development of intra-alveolar and interstitial fibrosis. The super anti-inflammatory and anti-fibrotic effects of curcumin ensure natural healing. Regular administration of curcumin curbs inflammation and fibrosis. Curcumin also ominously inhibited the expression of α-smooth muscle actin and Tenascin-C, key markers of myofibroblast activation.

Curcumin and Interleukin‐6 (IL‐6)

Curcumin is a most important bioactive compound of medicinal turmeric that applies its anti-inflammatory effects by crushing the many pro-inflammatory cytokines and chemokine’s in a number of cell types and pathologic conditions. Interleukin-6 (IL-6) plays central roles in various events during inflammation, the therapeutic effects of curcumin suggesting a role for intonation of IL-6 in anti-inflammatory effects of curcumin. Curcumin can be considered as probable therapy against IL-6 involved pathologic stats.

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