Have you ever wondered if your blood vessels have a lifecycle? Well, they surely do. In fact, a process known as angiogenesis runs constantly within your body and allows existing blood vessels to sprout new ones all the time. A layer of endothelial cells forms a cushion inside blood vessels. As part of angiogenesis, these cells may migrate and grow to form new capillaries either in the existing location or in places where they are needed. This process runs rapidly during a child’s growth spurt or when the body is recovering from a health condition and is in the healing phase.

The governing elements for angiogenesis are chemical signals that are generated by your body. Signals like VEGF are received by receptors present on the surface of endothelial cells, triggering them to grow new vessels. On the other hand, the body also generates signals that discourage the process of angiogenesis. These two types of chemical signals help maintain a balance so that blood vessels are generated only when needed and not in excess at any given time.

One of the most dreadful outcomes of a malfunction in this balancing act played out by your body is the swift development of malignant growths. When abnormal cancer cells develop within your body, they give rise to tumors. These tumors require a constant supply of blood to thrive which is why they begin sending out signals to your body to stimulate the angiogenesis process. As a result, the body creates new blood vessels around the tumor which feed it constantly thus allowing it to grow uninhibited. Similarly, these blood vessels make it easier for cancer cells to take over surrounding tissues as well and move around the rest of the body, forming colonies all over. This results in metastasis, a phenomenon that spells doom for cancer patients.

In most cancer treatment protocols, the use of angiogenesis inhibitor drugs is common. These drugs work well as they are able to stop the creation of new blood vessels and can, therefore, starve the tumor. This line of treatment focuses on cutting off the tumor’s nutrition supply instead of attempting to stop the development of tumor producing cells. Since chemical drugs are known to have side effects that can give birth to harsh symptoms, there is an increasing interest in finding natural substances that can inhibit angiogenesis.

One such substance, a polyphenolic pigment found in turmeric, has proven time and again that it can work just as effectively as any angiogenesis-inhibiting drug in the market. This natural wonder is known as curcumin. Curcumin has many therapeutic qualities including being a potent antioxidant, an anti-inflammatory agent, and a broad s[ectrum anti-microbial agent as well.

As an Angiogenesis Inhibitor Curcumin works as follows:

oncomin for cancer prevention

  1. VEGF is one of the primary signaling mechanisms that give rise to angiogenesis. Curcumin interferes in the activity of this chemical signal by hampering COX-2 and MAPK. It also reduces the expression of VEGF.
  2. Curcumin pulls down the level of expression of angiopoietin 1 and 2 in the abnormal cells that form the tumor. It also puts a barrier in the smooth VEGF production in the tumor cells by bringing down the expression of HIF1-alpha.
  3. Curcumin can ensure that blood vessel producing cells do not move towards malignant growths. By inhibiting the activity of proteins like u-PA and MMP curcumin successfully cuts down the generation of growth factors that eventually lead to the formation of new capillaries.
  4. Curcumin can bring down the effectiveness of adhesion molecules that are present on endothelial cells and which makes it possible for these cells to attach to other cells. This activity helps prevent the growth of a tumor as well as the process of metastasis.

In most of the forms of cancer, the beginning is marked by a small malignant growth that slowly grows in size and also leads to the formation of other growths all over the body. As explained above, it is the process of angiogenesis that works erratically to fuel such activity within your body which is why it is all the more important to find ways to put a brake on it. Oncomin, a curcumin enriched supplement created by Bagdara Farms is a perfect natural angiogenesis inhibiting remedy that has all the properties that make it safe for consumption.

How Curcumin from Bagdara Farms is Different?

  1. The curcumin used in Oncomin comes from a wild strand, making it much more effective.
  2. The curcumin used is grown organically
  3. The curcumin crop is not treated with artificial pesticides or fertilizers
  4. The curcumin used is not genetically modified.

4 thoughts on “How Curcumin’s Anti-Angiogenesis Properties Help Cancer Patients

  1. Hi, Can you suggest for first stage cancer to my friend he has bleeding 3 times in last 20 days , doctor says to test and this is first stage ? What can we do ? Please suggest and help me.

    1. Hello Mr Sanjay,
      Thank you for writing to us. We would need to talk on call to understand the problem better and for that we would request you to either share your number with us or you can call us on 9560254646, so that every detail can be given properly. We look forward to hearing from you.

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Clinical Trial & Our Product

Since health care & medicine is an industry, formulations are controlled through intellectual property rights denying easy access to common people and maintaining the buoyancy for the interest holders. Formula’s can be patented and that covers business interests that drive innovations these days.

So instead of conducting trials on the raw root, almost all companies promote clinically tested formulations of extracts to make it appear better then how the phytochemical was in its original state. Its like extracting an important organ from the body and then putting it on support system, expecting it to perform better in insolation then how it could perform when in it was in its natural form. The truth is, that the best way to consume a plant based medicine is in its raw form. Curcumin is one of the active ingredients in the root Curcuma Longa.

Since its more important to know what your food ate then what you ate, its important to know that the supplements you are using based on curcumin has curcumin from a gene modified variety of curcuma longa which suffers from an imbalance of every other mineral. You see a plant also behaves how a human body behaves when it is injected with steroids to gain muscle mass for body building purpose. The plants have higher levels of curcumin but all other secondary minerals found along curcumin in the plant get compromised as the plant can not feed all nutritions equally when it is designed to feed most of its nutrition towards developing higher levels of curcumin. It has severe side effects on the health of the plant and apparently on the people consuming such plants or extracts coming from these plants. However marketing and promotions have evolved to divert attention very wisely.

An extract of any herb can never be stored in its original state and hence needs base agents, preservatives which hardly leave it how it must be. We believe that access to medicine and healthcare is a basic right of every human and animal living on planet earth. Hence we do not first extract and then add preservatives or agents like pepperine to make the extract bio-available. This is the reason we never patent any of our products. We instead hand process the whole root we cultivate in our farms and share it with the people under different brand names for different health conditions based on the concentration of minerals present at testing. You can also buy the seed from us and cultivate it but it will certainly not be as potent as you get from us.

How potent is the active ingredient in the plant depends on the quality of seed, soil, water and environment. Our products work far better then most of the curcumin based supplements globally being used for Therapeutic benefits.

We do not intend to formulate or patent our products. So instead of choosing a supplement with an extract, choose wisely and go for the best and not the Cheapest.

All our products are cultivated, harvested, hand processed and distributed directly from our own farms to ensure that people who depend on our products for their acute and chronic problems get consistent supply of highest quality, ultra premium, medicinal grade, Non-GMO, Indigenous, Naturally enriched with curcumin, Wild Strand curcuma longa powder for therapeutic benefits. We cultivate this in the middle of a national park which happens to be the best breeding ground for Bengal tigers in India called Bandhavgarh.