SABOTAGING CERVICAL CANCER WITH CURCUMIN
In India, cervical cancer is responsible for approximately 6–29% of all cancers in women.
Studies suggest that Indian women, who account for at least one-fourth of the global disease burden, are not routinely screened.
This largely avertable disease is the second most common cause of cancer mortality among Indian women, with an estimated 1 lakh new cases in 2016 and about 1.04 lakh during 2020.
An estimated 5,70,000 women were diagnosed with cervical cancer worldwide and about 3,11, 000 women died from the disease.
What Is Cervical Cancer?
Cervical cancer is cancer that arises in the cervix of the uterus.
Long-lasting infection with certain types of human papillomavirus (HPV) is the chief cause of cervical cancer.
HPV is a common virus that is passed from one person to another during intercourse.
Is It Treatable?
When cervical cancer is detected early, it is highly treatable and associated with long survival and good quality of life.
Cervical Cancer is the only female cancer which is not only completely avertible but also completely mendable if detected and treated upon in the early stages.
The Magical Medicinal Turmeric To Rescue, Does It Help?
Curcumin in medicinal turmeric is said to slow down, destroy or prevent the growth of precancerous or cancer cells.
Destroys precancerous growth
The presence of abnormal cells of the cervix is considered precancerous cells.
Both invasive cervical cancers and precancerous cells have been resolutely associated with the presence of high-risk HPV.
Chemo-preventive and anti-tumorogenic
Curcumin found in medicinal turmeric functions as an:
1. Apoptotic,
2. Chemo-preventative,
3. Anti-tumorogenic molecule,
Suggesting that curcumin appears to affect cell viability and warrants inspecting as a potential chemo-preventative agent for cervical disease.
As an anti-inflammatory
According to https://cancerres.aacrjournals.org/content/65/9_Supplement/
As an anti-inflammatory and chemo-preventative agent, medicinal turmeric with curcumin is responsible for inhibiting a variety of anti-inflammatory molecules including:
(1) Phospholipase, (2) Lipo-oxygenase, (3) Cyclooxygenase 2,
(4) Leukotrienes, (5) Thromboxanes, (6) Prostaglandins,
(7) Nitric oxide, (8) Collagenase, (9) Elastase,
(10) Hyaluronidase, (11) Monocyte chemoattractant protein-I (MCP-I), (12) Interferon-inducible protein, (13) Tumor necrosis factor (TNF) and Interleukin-12 (IL-12)- All molecules linked with inflammation
Also, it has been shown to retain inhibitory effects on progression of many tumour cells by dipping cellular proliferation and inducing apoptosis in cervical cancer.
Curcumin treatment for individuals suffering from cancer of the cervix, is shown to inhibit transcription of HPV 16 E6/E7 as early as 6 h post-treatment, re-establishes the countenance of tumour inhibitor proteins p53, Rb, and PTPN13 [20].
It has the capability to mend the paclitaxel prompted apoptosis of HPV-positive human cervical cancer cell lines via the NF-κB, p53-caspase 3 pathway.
Curcumin promotes ER stress-mediated apoptosis in cervical cancer cells through increasing the cell type-specific ROS generation
Potential Anti-oxidant
What future FUTURE MEDICINE UK. says
https://www.futuremedicine.com/doi/full/10.2217/fon.15.166
Says that the natural herbal antioxidant curcumin found in medicinal turmeric may serve as a strong anti-HPV agent, which can be used, to either prevent HPV infection or simplify the effective treatment of cervical cancer by targeting and sensitizing cancer and cancer stem cells.
Conclusion
It is time to put behind the stigma, shame, and superstitions and make everyone aware about a cancer which is not only completely preventable but also curable.
Medicinal Turmeric has been shown to induce cytotoxic cell death in human cervical cancer cells.
Cervikil https://bagdarafarms.com/product/cervikil/ from Bagdara Farms is abundant in curcumin, a promising natural product is endowed with numerous therapeutic potentials including significant anticancer effects.
Cervikil rich in curcumin, the main bioactive ingredient of medicinal turmeric, has been revealed to possess various therapeutic potentials, such as anti-tumor, anti-atherosclerotic, anti-microbial, anti-oxidant, and anti-inflammatory to its credit.
After establishing itself as the number one herb, turmeric/curcumin is increasingly moving into functional supplements, it is one of the best gits to humankind, so use it wisely, and most importantly, choose wisely the correct curcumin supplement.