Curcumin Suppression of Cytokine Release and Cytokine Storm. Potential Therapy for Patients with Ebola and Other Severe Viral Infections (Reference:

Background: The terminal stage of Ebola and other viral diseases is often the onset of a cytokine storm, the massive overproduction of cytokines by the body’s immune system.

Materials and Methods: The actions of curcumin in suppressing cytokine release and cytokine storm are discussed.

Results: Curcumin blocks cytokine release, most importantly the key pro-inflammatory cytokines, interleukin-1, interleukin-6, and tumor necrosis factor-α. The suppression of cytokine release by curcumin correlates with clinical improvement in experimental models of disease conditions where a cytokine storm plays a significant role in mortality.

Conclusion: The use of curcumin should be investigated in patients with Severe Viral Infections like Corona (COVID-19).

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